The Hand in Multiple Epiphyseal Dysplasia

Multiple Epiphyseal Dysplasia (MED) is an uncommon anomaly of the bone and cartilage at the ends of the bones (epiphyses) in the growing child.  There are 6 primary types of Multiple Epiphyseal Dysplasia. All are transmitted in an autosomal dominant fashion except type 4. EDM1 is caused by a heterozygous mutation in the gene encoding […]

The Crooked Thumb

The process of limb development is truly amazing and unbelievably complex.  Developmental biologists and scientists help to explain these processes and our knowledge grows day by day.   As I explain to parents, what is truly remarkable is not that there is a child born with a limb difference but rather that it happen so […]